Why choose skin111?

Prices start from AED 490 (after discount).
Voted among the Top 6 Aesthetics Clinics in the GCC for 2021, 2022, 2023, and 2024.
Awarded Best Aesthetics Clinic in Dubai at MEA Business Awards, 2022 and 2023.
Uses high-quality, DHA/MOH-approved products from the USA, UK, Italy, and France.
Scientifically proven to be safe, effective, and reasonably long-lasting.
Guaranteed best prices for top-quality service and products.
Procedures and consultations are performed by DHA-certified doctors with a minimum of 8 years of experience.
Luxury clinics in Premium locations: DIFC and Nakheel Mall - Palm Jumeirah.
Open daily from 9 AM to 9 PM
Free valet parking
40% discount with SKIN111 loyalty card.
0% interest payment plans available.

What are Polynucleotides?

Polynucleotides are long-chain molecules made up of nucleotide monomers linked together. Each nucleotide consists of three main components: a nitrogenous base (adenine, thymine, cytosine, guanine, or uracil), a sugar molecule (ribose in RNA or deoxyribose in DNA), and one or more phosphate groups. These molecules form the backbone of DNA and RNA, which are vital for storing and transmitting genetic information and facilitating various cellular processes.

In aesthetic medicine, Polynucleotide treatment utilizes natural DNA fragments, often derived from sources like salmon or trout, to promote skin regeneration and healing. By injecting these polynucleotides into the skin, the treatment stimulates collagen production, improves skin texture and elasticity, and boosts hydration. This minimally invasive procedure is particularly effective for rejuvenating aging or damaged skin, reducing fine lines, and restoring a youthful, radiant complexion. With little to no downtime, polynucleotide therapy offers a natural and long-lasting solution for those seeking comprehensive skin revitalization.

Benefits of Polynucleotides treatment

Polynucleotide treatment offers a comprehensive range of benefits for those seeking skin rejuvenation and overall skin health improvement. Some of the key advantages include:

Skin rejuvenation: Polynucleotides enhance collagen and elastin production, leading to improved skin texture, elasticity, and firmness. This helps diminish the appearance of fine lines and wrinkles, offering a smoother, more youthful complexion.
Hydration and moisturization: The treatment significantly boosts skin hydration by drawing in water molecules, resulting in a fuller, more moisturized look.
Anti-inflammatory effects: Polynucleotides possess natural anti-inflammatory properties, reducing redness, swelling, and irritation. This makes the treatment particularly beneficial for conditions such as acne, rosacea, and sensitive skin.
Tissue repair and regeneration: By promoting wound healing and repairing damaged skin cells, polynucleotide therapy effectively treats acne scars, stretch marks, and other skin imperfections.
Antioxidant protection: The treatment provides antioxidant protection, shielding the skin from oxidative stress caused by environmental factors such as UV exposure and pollution, helping to prevent premature aging.
Minimally invasive with little downtime: Polynucleotide treatments are non-surgical and require minimal recovery time, making them a convenient option for individuals with busy lifestyles.
Natural and long-lasting results: This therapy offers natural-looking, gradual improvements that can last for months to years, depending on individual skin conditions.
Safe and well-tolerated: Polynucleotide treatments use DNA fragments from natural sources like salmon, which are biocompatible and generally well-tolerated by the skin.

What is Polynucleotide treatment?

Polynucleotide treatment, also known as PN or PDRN (polydeoxyribonucleotide) therapy, is a cutting-edge cosmetic and medical procedure offered at Skin111. This treatment involves the injection of polynucleotides natural DNA fragments extracted primarily from sources like salmon or trout—into the skin to promote regeneration and repair. By harnessing the unique regenerative properties of polynucleotides, this advanced therapy enhances skin quality, texture, and elasticity.

At SKIN111, polynucleotide therapy is designed to improve hydration levels, boost cellular regeneration, and amplify the skin's natural healing abilities. It is an effective anti-aging solution that helps reduce the appearance of fine lines and wrinkles, offering a non-invasive way to achieve a youthful, vibrant complexion. Whether you seek skin rejuvenation or overall revitalization, PN therapy at Skin111 provides long-lasting, natural results with minimal downtime.

How do Polynucleotide injections work for skin rejuvenation?

Polynucleotide injections work by introducing natural DNA fragments into the skin, which activate the body’s natural healing and regenerative processes. These injections contain polynucleotides—biological molecules that promote tissue repair, improve cell turnover, and enhance skin hydration.

When injected into the skin, polynucleotides stimulate fibroblasts, the cells responsible for producing collagen and elastin, two essential proteins that maintain skin firmness and elasticity. This leads to increased collagen production, improved skin texture, and enhanced elasticity over time. Polynucleotides also have powerful anti-inflammatory and antioxidant properties, which help repair damaged skin and reduce the effects of aging.

The result is firmer, smoother, and more hydrated skin, with a reduction in fine lines, wrinkles, and other signs of aging. With minimal downtime, polynucleotide injections offer a natural and effective approach to skin rejuvenation, making them an ideal choice for those seeking long-lasting, youthful results.

Polynucleotide treatment procedure

The polynucleotide treatment procedure at SKIN111 is a minimally invasive process designed to enhance and repair the skin through a series of targeted injections. Here’s an overview of what to expect:

Consultation: Your journey begins with a thorough consultation at SKIN111, where our skincare professionals assess your skin condition and discuss your aesthetic goals. We will determine if polynucleotide treatment is suitable for your needs.
Preparation: Before the procedure, your skin will be cleansed to ensure optimal results. At Skin111, we apply a local anesthetic to minimize any discomfort during the treatment.
Injection Technique: Using fine needles or a micro-needling device, our skilled practitioners administer a polynucleotide solution, which consists of natural DNA fragments, into the skin. The solution is injected at various locations throughout the treatment area to achieve uniform coverage and the best possible results.
Injection depth: The depth of each injection is tailored to address specific skin issues, such as fine lines, wrinkles, or scars, and is adjusted based on the area being treated. Our experts ensure precise application to meet your individual needs.
Duration: The entire procedure generally takes about 20-30 minutes, depending on the size and complexity of the treatment area.

Polynucleotides treatment aftercare

roper aftercare following a polynucleotide treatment is crucial for achieving the best results and ensuring a smooth recovery. Here are some key aftercare guidelines to follow:

Avoid direct sunlight: Refrain from exposing the treated areas to direct sunlight for at least 1-2 weeks. Use a broad-spectrum sunscreen with a high SPF to protect your skin if sun exposure is unavoidable.
Gentle skincare routine: Use mild, non-irritating skincare products on the treated areas. Avoid products with active ingredients like retinoids, acids, or exfoliants for the first week post-treatment.
Avoid heat and sweating: Steer clear of hot baths, saunas, and intense exercise that could cause excessive sweating for the first 48 hours. Heat and sweat can increase the risk of irritation and impact the healing process.
Hydrate: Maintain proper hydration by drinking plenty of water. This helps support the skin’s healing process and enhances the effects of the treatment.
Avoid touching or scratching: Do not touch, rub, or scratch the treated areas. This helps prevent infection and ensures that the polynucleotide solution remains effective.
Refrain from makeup for 24-48 hours: Skip applying makeup and skincare products during the first 24 to 48 hours after the treatment to facilitate skin healing and minimize infection risks.
Limit sun exposure: Shield the treated skin from direct sunlight and UV rays by applying sunscreen (SPF 30 or above) and wearing a wide-brimmed hat for at least 1-2 weeks to ensure proper healing.
Avoid strenuous activities: Stay away from intense exercise, saunas, hot baths, or steam rooms for 24-48 hours, since sweating and heat can exacerbate redness and swelling.
Apply cold compress: If you experience swelling or redness, use a cold compress or an ice pack wrapped in a clean cloth intermittently to alleviate discomfort and soothe the area.
Follow post-treatment instructions: Adhere to any additional aftercare instructions provided by your skincare professional at SKIN111. This may include applying specific creams or avoiding certain activities.
Monitor for adverse reactions: While rare, if you experience any severe redness, swelling, or signs of infection, contact SKIN111 immediately for further guidance.
Schedule follow-up appointments: Attend any recommended follow-up appointments to monitor your progress and discuss any concerns with your skincare professional.

By following these aftercare guidelines, you can help ensure a smooth recovery and maximize the benefits of your polynucleotide treatment at SKIN111.

Polynucleotides treatment cost in Dubai, UAE

At SKIN111, we offer Salmon DNA (a type of polynucleotide) starting from AED 490 per 1ml, with a best-price guarantee. The final cost will depend on the treatment area and the required number of milliliters.

We provide a free consultation with our experienced doctors, who will assess your needs and create a personalized treatment plan. After the consultation, our team will determine the most suitable pricing based on your treatment requirements.

Polynucleotides treatment before and after

Polynucleotides treatment: FAQs

Is polynucleotide injection treatment painful?

Polynucleotide injection treatment is generally considered to be only mildly uncomfortable for most individuals. The level of discomfort can vary depending on factors such as individual pain tolerance, the sensitivity of the area being treated. To minimize discomfort, many clinics apply a topical numbing cream before the procedure, making the experience more comfortable for the patients.

How long do the effects of polynucleotide injections last?

Polynucleotide injections usually last 4 to 6 months, but this can vary based on skin type, age, lifestyle, and treatment area. Follow-up sessions may be recommended for better results, with maintenance treatments every few months.

How many sessions are needed for optimal results?

To achieve the best outcomes, it is generally advised to start with a series of 2-4 sessions scheduled 2-4 weeks apart. After this, maintenance treatments are typically recommended every 4 to 6 months to maintain the enhancements in skin quality, texture, and hydration levels. The number of sessions and maintenance schedule can be customized based on individual needs.

Can I undergo polynucleotide treatment if I have sensitive skin?

Yes, you can receive polynucleotide treatment. These treatments are typically safe for sensitive skin as they are made from natural DNA derivatives and are gentle and healing. Polynucleotides can help with skin healing, inflammation reduction, and hydration improvement, which are all beneficial for sensitive skin. It is recommended to consult with a qualified doctor to determine the best treatment plan for your skin's unique needs.

How soon can I apply makeup after the treatment?

Makeup can typically be applied 24 to 48 hours after receiving a polynucleotide injection treatment.

Polynucleotides Treatment in Dubai, UAE